Prof. Marcos G. Suero

Catalysis

Group Leader:

Marcos García Suero

Administrative Support:

Paula Segovia

Postdoctoral Researchers:

Liyin Jiang / Hangfei Tu / Wei Jie Teo / Marten L. Ploeger / Leonardo J. Nannini

PhD Students:

Pau Sarró / Aliénor Jeandin / Èric Cots / Eric Palomo / Valero Gimeno Alfonso / Josep Esteve Guasch

Summary

The main objective of Dr. Suero is to catalytically generate reactive carbon species not yet explored and study their behavior on organic compounds. His goal is to discover new rules of reactivity of carbon, not only for the design and discovery of new chemical reactions, but also for its use to build molecular complexity. The group has been a pioneer in the catalytic generation of diazomethyl radicals as direct equivalents of monovalent carbine species. This discovery allows the design of innovative disconnection strategies for the construction of chiral centers in drugs, agrochemicals and materials. In addition, the group is interested in the use of highthroughput techniques for the synthesis of libraries of bioactive molecules that cannot be obtained by conventional routes, precision medicine with PET imaging and in the development of new chemical reactions with application in chemical biology.

Publications

β‐Diazocarbonyl compounds: synthesis and their Rh(II)‐catalyzed 1,3 C‐H insertions
Jiang, L.; Wang, Z.; Armstrong, M.; Suero, M. G.
Angew. Chem. Int. Ed. 2021133 (11), 6242-6249 (Chosen as “hot paper” by the editors for its importance and high interest)

 

Projects

Late-need
Late-stage diazomethylations to impact urgent & unmet medical needs
Ministerio de Ciencia e Innovación | Ref: PDC2021-121180-I00

CARBYNE
New carbon reactivity rules for molecular editing

ERC Consolidator Grant | Ref: 865554

CARBYNOID
New carbyne transfer catalysis in organic chemistry

Ministerio de Ciencia e Innovación | Ref: PID2019-104101GB-I00

Síntesis de nuevos derivados antimaláricos a través de una nueva reacción de borilación
BBVA | Ref: CBB_QUI_0130

 

Theses Supervised

Èric Cots
December 20th, 2021
Universitat Rovira i Virgili
«Understanding Iodine (I/III) Catalysis: From Racemic to Enantioselective Transformations»