Prof. Ruben Martin


Group Leader:

Ruben Martin, ICREA Professor

Administrative Support:

Ingrid Mateu

Postdoctoral Researchers:

Jacob Davies / Ciro Romano / Victoria Rendon (until Sep.) / Christopher Sandford (until Apr.) / Santosh C. Gadekar / Jesus Rodrigalvarez / Franz-Lucas Haut / Riccardo Salvartore / Robert Freud / Mattew Wakelling / Jesus San José (until Feb.) / Hongfei Yin / Riccardo Mega / Raul Martin / Roman Abrams

PhD students:

Craig Day / Laura Talavera / Carlota Odena / Fei Cong / Xinyang Lyu / Dmitry Zimin / Wen-Jun Yue / Julien Lyonnet / Jinhong Chen

Lab technician:

David Sádaba

Visiting Researchers:

Juzeng An (Jan. – Sep.)


The research of Prof. Martin focuses on discovering the potential of catalytic functionalization of raw materials for the synthesis of valuable compounds from simple and abundant precursors. They have contributed extensively to the catalytic functionalization of C-O and C-H bonds, as well as to the fixation of CO2 to organic matter. They have described a catalytic technology capable of fixing carbon dioxide in saturated and unsaturated hydrocarbons to prepare fatty acids, key parts in the manufacture of polymers, detergents, cosmetics, and pharmaceuticals.


Recent developments in nickel-catalyzed cross-coupling reactions via C–O functionalization
Odena, C.; Talavera, L.; Martín, R.
Revista de la Societat Catalana de Química 2021, 86-100

Nickel-Catalyzed Ipso/Ortho Difunctionalization of Aryl Bromides with Alkynes and Alkyl Bromides via a Vinyl-to-Aryl 1,4-Hydride Shift
He, Y.; Börjesson, M.; Song, H.; Xue, Y.; Zeng, D.; Martin, R.; Zhu, S.
J. Am. Chem. Soc. 2021143 (48), 20064–20070

The road to industrialization of fine chemical carboxylation reactions
Davies, J.; Lyonnet, J. R.; Zimin, D. P.; Martin, R.
Chem 20217 (11), 2927-2942


Cluster Preface: Modern Nickel-Catalyzed Reactions
Martin, R.; Molander, G. A.
Synlett 202132 (15), 1492-1493

Nickel-Catalyzed Reductive Carboxylation and Amidation Reactions
Tortajada, A.; Börjesson, M.; Martin, R.
Acc. Chem. Res. 202154 (20), 3941–3952

Ligand-Controlled Regiodivergent Catalytic Amidation of Unactivated Secondary Alkyl Bromides
Tortajada, A.; Menezes Correia, J. T.; Serrano, E.; Monleón, A.; Tampieri, A.; Day, C. S.; Juliá-Hernández, F.; Martin, R.
ACS Catal. 202111, 10223–10227

Low-Valent Tungsten Catalysis Enables Site-Selective Isomerization–Hydroboration of Unactivated Alkenes
Jankins, T.; Martin-Montero, R.; Cooper, P.; Martin, R.; Engle, K.
J. Am. Chem. Soc. 2021143 (37), 14981–14986

Mechanistic Studies into Visible Light-Driven Carboxylation of Aryl Halides/Triflates by the Combined Use of Palladium and Photoredox Catalysts
Toriumi, N.; Shimomaki, K.; Caner, J.; Murata, K.; Martin, R.; Iwasawa, N.
Bull. Chem. Soc. Jpn. 202194 (7), 1846-1853

Site-Selective Defluorinative sp3 C–H Alkylation of Secondary Amides
Yue, W. J.; Day, C. S.; Martin, R.
J. Am. Chem. Soc. 2021143 (17), 6395–6400

Nickel-Catalyzed Photodehalogenation of Aryl Bromides
Higginson, B.; Sanjosé-Orduna, J.; Gu, Y.; Martin, R.
Synlett 202132 (16), 1633-1636

Ni-Catalyzed Carboxylation of Aziridines en Route to β-Amino Acids
Davies, J.; Janssen-Müller, D.; Zimin, D. P.; Day, C. S.; Yanagi, T.; Elfert, J.; Martin, R.
J. Am. Chem. Soc. 2021143 (13), 4949–4954

sp3 Bis‐Organometallic Reagents via Catalytic 1,1‐Difunctionalization of Unactivated Olefins
Sun, S. Z.; Talavera, L.; Spiess, P.; Day, C.; Martin, R.
Angew. Chem. Int. Ed. 202160 (21), 11740-11744

Deciphering the dichotomy exerted by Zn(II) in the catalytic sp2 C–O bond functionalization of aryl esters at the molecular level
Day, C. S.; Somerville, R. J.; Martin, R.
Nat Catal 20214, 124–133


Escaping from Flatland by “de novo” Catalytic Decarboxylation Techniques
ERC Advanced Grant | Ref: 883756

Cooperation towards a sustainable chemical industry
MSCA ITN | Ref: 859910 Web page

Tecnologías Químicas para la Valorización de Residuos Industriales en los Pirineos
Collaborative Projects | Ref: EFA308/19 Web page

Nickel-catalyzed bond-formation reactions with native functional groups
Ministerio | Ref: PGC2018-096839-B-I00

Grup d’Activació Catalítica d’Enllaços Inerts
AGAUR | Ref: SGR 938


Theses Supervised

Raul Martin Montero
January 15th, 2021
Universitat Rovira I Virgili
“Functionalization of Strong Sigma Bonds by Nickel and Tungsten Catalysis”



Prof. Ruben Martin in the Forbes TOP 50 Awarded Spaniards list

Understanding catalytic couplings: not all synergies are simple